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Mechanism of Action

Keratolytic Effects

Also: keratolytic, exfoliation, desquamation, scale removal

By Cosmetic Peat Editorial Team Updated June 2026

Skin constantly sheds its outer layer. Normally this happens invisibly — dead cells detach one by one and wash away. But in conditions like psoriasis, dandruff, and seborrheic dermatitis, the process goes wrong. Cells pile up faster than they shed, forming thick plaques, flakes, or scales. Keratolytic agents break these accumulations down — and peat does it through three compounds working together.

How it works

Think of dead skin cells as tiles held together by mortar. To remove them, you need to dissolve the mortar. Peat attacks these bonds from three angles simultaneously:

Humic acids soften keratin protein through direct interaction with its structure — loosening the “mortar” between dead cells. This is a gentle, gradual action rather than the aggressive stripping of a chemical peel.

Organic acids in peat work like a mild version of the alpha-hydroxy acids (AHAs) used in cosmetic exfoliants. They weaken the bonds between corneocytes — the flat, dead cells of the outermost skin layer — allowing them to detach more easily.

Sulfur compounds break the disulfide bonds that cross-link keratin proteins. This is the same mechanism behind sulfur-based dandruff shampoos and psoriasis treatments — peat delivers it alongside anti-inflammatory and antimicrobial compounds rather than in isolation.

The result is gentle but effective exfoliation. A 12-week study using peat extract showed visible reduction in scalp squames (flakes) under microphotography (Bovcon 2012). Clinical observations from psoriasis patients report plaque softening and reduction during peat treatment courses (Leibaschoff 2005).

Why it matters

Keratolytic action is especially important because dead skin buildup is both a symptom and a barrier to treatment. A thick psoriatic plaque blocks topical anti-inflammatory compounds from reaching the living skin beneath it. By softening and removing the buildup, peat’s keratolytic mechanism clears the way for its own anti-inflammatory and moisturizing compounds to work on the underlying problem.

How It Works

Targets Keratin protein in stratum corneum
Pathway Softening and dissolution of intercellular bonds in dead skin layer

Active Substances

Compounds that exhibit this mechanism

Conditions It Helps

Products That Deliver It

Peat Balneotherapy Peat Body Wraps Peat Compresses Peat Cream / Lotion Peat Face Masks Peat Mud Pack Peat Scalp Treatments Peat Shampoo

References

4 papers
Clinical observation of plaque reduction in peat-treated patients
Bovcon, Maria Laura, Cisterna, Miguel (2012). Peat for Hair Treatment
Microphotography showed reduction in scalp squames after 12-week peat extract treatment
Błońska-Sikora, Ewelina, Klimek-Szczykutowicz, M. (2024). Potential Possibilities of Using Peat, Humic Substances, and Sulfurous Waters in Cosmetology — Applied Sciences
Review: keratolytic properties of peat humic substances in cosmetology
Uwe Wollina (2009). Peat: A Natural Source for Dermatocosmetics and Dermatotherapeutics — Journal of Cutaneous and Aesthetic Surgery
Review: peat application helps with pustule resolution and scaling in inflammatory skin conditions