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The efficacy of balneotherapy and mud-pack therapy in patients with knee osteoarthritis

rct Grade B 2007 n=80
Authors: Evcik, D., Kavuncu, V., Yeter, A., Yigit, I.
Journal: Joint Bone Spine 74 : 60-65
DOI: 10.1016/j.jbspin.2006.03.009
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Key Findings

  • 80 patients with knee OA randomized to 3 groups: balneotherapy (n=25), mud-pack (n=29), hot-pack control (n=26)
  • All treatments: 20 min, once daily, 5×/week, 10 sessions total
  • Pain assessed by VAS and WOMAC pain scale
  • Functional capacity assessed by WOMAC functional capacity and global index
  • Quality of life assessed by Nottingham Health Profile (NHP)
  • Both balneotherapy and mud-pack groups showed significant improvement over hot-pack control

One of the few trials that tests balneotherapy and mud-pack therapy side by side against the same control. Published in Joint Bone Spine, this three-arm RCT is valuable precisely because it can distinguish the contribution of immersion (balneotherapy) from topical application (mud-pack) — two delivery routes that are often grouped together in reviews but deliver peat bioactives differently.

Study Design

80 patients with knee osteoarthritis were randomized into three groups:

  • Balneotherapy (n=25) — immersion in peloid bath
  • Mud-pack (n=29) — topical peat pack applied to the knee
  • Hot-pack control (n=26) — heat only, no bioactive content

All groups received 10 sessions, 20 minutes each, once daily, 5 days per week over 2 weeks. This matched protocol isolates the effect of the peat itself rather than differences in treatment intensity.

What Was Measured

  • Pain: VAS (Visual Analogue Scale) and WOMAC pain subscale
  • Function: WOMAC functional capacity and global index
  • Quality of life: Nottingham Health Profile (NHP)

Using three independent instruments for pain and function strengthens confidence in the findings.

Key Findings

Both the balneotherapy group and the mud-pack group showed significant improvements in pain, functional capacity, and quality of life compared to the hot-pack control group. Neither peat-based treatment was clearly superior to the other — both outperformed heat alone. This is the central result: whether you immerse a joint in peat or apply a peat pack topically, the outcome in knee OA exceeds what heat alone achieves.

What It Adds to the Evidence Base

Most mud/peat therapy trials test a single delivery method. This trial’s three-arm design confirms that the chemical benefit of peat is not delivery-route-specific — it manifests whether peat contacts the skin through immersion or direct pack application. That finding is relevant to product development: topical peat products can legitimately claim the same mechanism as clinical balneotherapy, even if the intensity differs.

knee-OARCTbalneotherapymud-packWOMACVASquality-of-life