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Balneology and spa treatments in dermatology: The european point of view

review Grade D 1994 Open access
Authors: Lotti, T., Freedman, D.
Journal: Journal of the European Academy of Dermatology and Venereology (JEADV) 3 (4) : 449-450
DOI: 10.1111/j.1468-3083.1994.tb00398.x
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Key Findings

  • Editorial framing dermatologic balneology as an established European therapeutic tradition, contrasted with a more skeptical American view
  • Sulphuric spa waters show a dose-dependent inhibitory effect on stimulated human peripheral blood lymphocytes in vitro, with strong inhibition of CD3-activated T lymphocytes
  • Sulphureous spa water immersion inhibits IL-2 and IFN-gamma release from Th1 lymphocytes — a proposed local immunomodulating effect relevant to inflammatory skin disease
  • Integrating sulphur balneology with phototherapy is described as an effective psoriasis treatment in Italy, Iceland, and at the Dead Sea
  • Montecatini (Italy) mud-baths raise plasma beta-endorphin levels in a way qualitatively different from heat-shock alone, offered as a partial mechanistic explanation for balneotherapy's pain and immune effects

A short 1994 editorial by Lotti and Freedman framing the European tradition of dermatologic balneology against then-prevailing American skepticism, and summarizing the immunological rationale available at the time: sulphur-rich spa water inhibits T-lymphocyte proliferation and Th1 cytokine release (IL-2, IFN-gamma), a mechanism proposed to explain balneotherapy’s benefit in inflammatory skin disease. Not peat-specific — it covers mineral spa waters generally — but it is a foundational, frequently-cited early source for the immunomodulatory rationale behind balneotherapy in psoriasis, and is read here as background support rather than peat-specific evidence.

The source is a scanned print original with visible OCR artifacts; the findings above were reconstructed from the abstract and clearly legible body sentences, with ambiguous OCR passages set aside.

balneologydermatologypsoriasisimmunomodulatorysulphur-waterrevieweurope