Systemic Toxicity and Dermal Irritation of Tołpa Peat Preparation
in-vitro Grade C 1993
Authors: Czyzewska-Szafran, H., Jastrzebski, Z., Sołtysiak-Pawluczuk, D., Wutkiewicz, M., Jedrych, A., Remiszewska, M.
Journal: Acta Poloniae Pharmaceutica 50 (4-5) : 373-377
PubMed: PMID 8036923
Key Findings
- Systemic toxicity of Tołpa Peat Preparation (TPP) assessed in rats and rabbits across acute and chronic dosing
- Dermal irritation tested directly on rabbit skin
- TPP was well tolerated in both species — no hematologic, liver, or kidney abnormalities
- No local dermal irritation was found
- The authors conclude TPP may be considered practically non-toxic
An animal toxicology study establishing that Tołpa Peat Preparation — a specific, standardized peat-derived preparation, not peat in general — is well tolerated systemically in rats and rabbits and produces no dermal irritation on direct skin testing. This is foundational safety data behind TPP’s status as a registered preparation in Poland, and is cited here as reassuring toxicology background rather than as a formal safety claim. Abstract-only sourcing; no full text was located.
tpptoxicologysafetydermal-irritationanimal-study